The average bus between Durham and Pittsburgh takes 14h 4m and the fastest bus takes 13h. The bus service runs several times per day from Durham to Pittsburgh. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Durham and Pittsburgh. The earliest departure is at 2:40 AM at night, and the last departure from Durham is at 9:15 PM which arrives into Pittsburgh at 10:15 AM. All services require a transfer, and take on average 14h 4m. The schedules shown below are for the next available departures.

15h 10m • 1 change

14h 40m • 1 change
Arrives next day

13h • 1 change

15h 10m • 1 change

14h 40m • 1 change
Arrives next day

14h 30m • 1 change
Arrives next day

13h • 1 change

14h • 1 change

14h 40m • 1 change
Arrives next day

14h 30m • 1 change
Arrives next day

13h • 1 change

14h • 1 change

14h 40m • 1 change
Arrives next day

14h 30m • 1 change
Arrives next day

13h • 1 change
Want to know about travelling from Durham to Pittsburgh? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Durham to Pittsburgh. However, there are services departing from Durham station and arriving at Pittsburgh station via Washington Union Station station. The journey, including transfers, takes approximately 14h 4m.
Durham to Pittsburgh bus services, operated by Greyhound USA, depart from Durham station.
Durham to Pittsburgh bus services, operated by Greyhound USA, arrive at Pittsburgh Intermodal Station.
Book your Durham to Pittsburgh bus tickets online with Greyhound USA and Flixbus USA.
The distance between Durham and Pittsburgh is 503.6 km. The road distance is 797 km.
You can take a bus from Durham to Pittsburgh Intermodal Station via Washington Union Station in around 11h 30m.