Durham to Pittsburgh Buses

Durham to Pittsburgh buses

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Trip Overview

The average bus between Durham and Pittsburgh takes 14h 44m and the fastest bus takes 12h 15m. The bus service runs several times per day from Durham to Pittsburgh. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

14h 44m
Duration: 493 mi
Distance: $105
Average price: 3 times a day
Frequency

Bus

best

Take the bus from Durham to Washington Union Stationbus FlixBus N2471 / ...
Take the bus from Washington Union Station to Pittsburgh Intermodal Stationbus Greyhound US0164 / ...

11h 55m

$77–134

Durham to Pittsburgh bus times

Buses run 3 times a day between Durham and Pittsburgh. The earliest departure is at 1:15 AM at night, and the last departure from Durham is at 9:15 PM which arrives into Pittsburgh at 1:30 PM. All services require a transfer, and take on average 14h 44m. The schedules shown below are for the next available departures.

Departing Wednesday, October 28, 2026

9:00 AM → 11:50 PM
14h 50m • 1 change

Departing Thursday, October 29, 2026

2:15 AM → 5:25 PM
15h 10m • 1 change
9:00 AM → 11:50 PM
14h 50m • 1 change
5:45 PM → 7:35 AM
Arrives next day
13h 50m • 1 change
9:15 PM → 1:30 PM
Arrives next day
16h 15m • 1 change

Departing Friday, October 30, 2026

3:50 AM → 5:25 PM
13h 35m • 1 change
9:00 AM → 11:50 PM
14h 50m • 1 change
5:45 PM → 7:35 AM
Arrives next day
13h 50m • 1 change
9:15 PM → 1:30 PM
Arrives next day
16h 15m • 1 change

Departing Saturday, October 31, 2026

3:50 AM → 5:25 PM
13h 35m • 1 change
9:00 AM → 11:50 PM
14h 50m • 1 change
5:45 PM → 6:35 AM
Arrives next day
13h 50m • 1 change

Departing Sunday, November 1, 2026

1:15 AM → 1:30 PM
12h 15m • 1 change
2:50 AM → 5:45 PM
14h 55m • 1 change
8:00 AM → 11:50 PM
15h 50m • 1 change
5:45 PM → 7:35 AM
Arrives next day
13h 50m • 1 change
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Departing Monday, November 2, 2026

9:00 AM → 11:50 PM
14h 50m • 1 change
9:15 PM → 1:30 PM
Arrives next day
16h 15m • 1 change

Departing Tuesday, November 3, 2026

9:00 AM → 11:50 PM
14h 50m • 1 change

Frequently asked questions

Want to know about travelling from Durham to Pittsburgh? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Trip Overview

Bus