Rome2Rio

Durham to Philadelphia buses

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Trip Overview

The average bus between Durham and Philadelphia takes 10h 42m and the fastest bus takes 9h 10m. The bus service runs several times per day from Durham to Philadelphia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

10h 42m
Duration
396 mi
Distance
$82
Average price
3 times a day
Frequency

Durham to Philadelphia bus times

Buses run 3 times a day between Durham and Philadelphia. The earliest departure is at 2:15 AM at night, and the last departure from Durham is at 9:15 PM which arrives into Philadelphia at 6:45 AM. All services require a transfer, and take on average 10h 42m. The schedules shown below are for the next available departures.

Departing Sunday, November 15, 2026

  •  → 

    Arrives next day

    Flixbus USAGreyhound USA9h 30m • 1 change

Departing Monday, November 16, 2026

  •  → 

    Flixbus USAFlixbus USA9h 30m • 1 change
  •  → 

    Flixbus USAFlixbus USA9h 10m • 1 change
  •  → 

    Greyhound USAGreyhound USA13h 30m • 1 change
  •  → 

    Arrives next day

    Flixbus USAGreyhound USA9h 30m • 1 change

Departing Tuesday, November 17, 2026

  •  → 

    Flixbus USAFlixbus USA10h 45m • 1 change
  •  → 

    Greyhound USAGreyhound USA13h 30m • 1 change

Departing Wednesday, November 18, 2026

  •  → 

    Flixbus USAFlixbus USA10h 45m • 1 change
  •  → 

    Greyhound USAGreyhound USA13h 30m • 1 change

Departing Thursday, November 19, 2026

  •  → 

    Flixbus USAFlixbus USA9h 30m • 1 change
  •  → 

    Greyhound USAGreyhound USA13h 30m • 1 change
  •  → 

    Arrives next day

    Flixbus USAGreyhound USA9h 30m • 1 change

Departing Friday, November 20, 2026

  •  → 

    Flixbus USAFlixbus USA9h 30m • 1 change
  •  → 

    Flixbus USAFlixbus USA9h 10m • 1 change
  •  → 

    Greyhound USAGreyhound USA13h 30m • 1 change
  •  → 

    Arrives next day

    Flixbus USAGreyhound USA9h 30m • 1 change

Departing Saturday, November 21, 2026

  •  → 

    Flixbus USAFlixbus USA9h 30m • 1 change
  •  → 

    Flixbus USAFlixbus USA9h 10m • 1 change
  •  → 

    Greyhound USAGreyhound USA13h 30m • 1 change

Frequently asked questions

Want to know about travelling from Durham to Philadelphia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Durham to Philadelphia.ExpandLaunch map view
  • Distance: 396.4 mi
  • Duration: 10h 42m

What companies run services between Durham, NC, USA and Philadelphia, PA, USA?

You can take a bus from Durham to Philadelphia Bus Station via Washington Union Station in around 9h 20m.

Operators