The average bus between Duke University and Chicago takes 27h 4m and the fastest bus takes 26h 18m. The bus service runs several times per day from Duke University to Chicago. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Duke University and Chicago. The earliest departure is at 8:40 AM in the morning, and the last departure from Duke University is at 4:41 PM which arrives into Chicago at 8:05 PM. All services require a transfer at Flowers Dr at Duke Gardens and take an average of 27h 4m. The schedules shown below are for the next available departures.
Arrives next day


25h 19m • 2 changes
Arrives next day


27h 24m • 2 changes
Arrives next day


25h 19m • 2 changes
Arrives next day


27h 24m • 2 changes
Arrives next day


25h 19m • 2 changes
Arrives next day


27h 24m • 2 changes
Want to know about travelling from Duke University to Chicago? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Duke University to Chicago. However, there are services departing from Duke University station and arriving at Chicago station via Washington Union Station station. The journey, including transfers, takes approximately 27h 4m.
Duke University to Chicago bus services, operated by GoDurham, depart from Durham station.
Duke University to Chicago bus services, operated by GoDurham, arrive at Chicago Bus Station.
The distance between Duke University and Chicago is 994.6 km. The road distance is 1,570 km.
You can take a vehicle from Duke University to Chicago Bus Station via Flowers Dr at Duke Gardens, Durham Station, Durham, and Washington Union Station in around 24h 59m.