Rome2Rio

Downingtown to Ithaca buses

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Trip Overview

The average bus between Downingtown and Ithaca takes 9h 40m and the fastest bus takes 9h 28m. The bus runs, on average, 4 times per week from Downingtown to Ithaca. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

9h 40m
Duration
341 mi
Distance
$73
Average price
4 times a week
Frequency

Downingtown to Ithaca bus times

Buses run 4 times a week between Downingtown and Ithaca. The earliest departure is at 6:45 PM in the evening, and the last departure from Downingtown is at 7:31 PM which arrives into Ithaca at 5:00 AM. All services require a transfer at West Chester Transit Center and take an average of 9h 40m. The schedules shown below are for the next available departures.

Departing Sunday, November 15, 2026

  •  → 

    Arrives next day

    SEPTASEPTASEPTAFlixbus USAFlixbus USA10h 14m • 4 changes

Departing Monday, November 16, 2026

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    Arrives next day

    SEPTASEPTASEPTAFlixbus USAFlixbus USA9h 28m • 4 changes

Departing Thursday, November 19, 2026

  •  → 

    Arrives next day

    SEPTASEPTASEPTAFlixbus USAFlixbus USA9h 28m • 4 changes

Departing Friday, November 20, 2026

  •  → 

    Arrives next day

    SEPTASEPTASEPTAFlixbus USAFlixbus USA9h 28m • 4 changes

Frequently asked questions

Want to know about travelling from Downingtown to Ithaca? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Downingtown to Ithaca.ExpandLaunch map view
  • Distance: 341 mi
  • Duration: 9h 40m

What companies run services between Downingtown, PA, USA and Ithaca, NY, USA?

You can take a bus from Lancaster Av & Green St - MBNS to Ithaca via West Chester Transit Center, 69th St Transit Center, 69th St Transit Center South Terminal, Chestnut St & 12th St, Philadelphia Bus Station, and Newark Penn Station in around 10h 17m.

Operators