The average bus between Des Moines and Mena takes 12h 54m and the fastest bus takes 11h 15m. The bus service runs several times per day from Des Moines to Mena. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Des Moines and Mena. The earliest departure is at 6:30 PM in the evening, and the last departure from Des Moines is at 11:45 PM which arrives into Mena at 2:35 PM. All services require a transfer, and take on average 12h 54m. The schedules shown below are for the next available departures.
Arrives next day

11h 15m • 1 change
Arrives next day

14h 50m • 1 change
Arrives next day

11h 15m • 1 change
Arrives next day

14h 50m • 1 change
Arrives next day

11h 15m • 1 change
Arrives next day

14h 50m • 1 change
Arrives next day

11h 15m • 1 change
Arrives next day

14h 50m • 1 change
Arrives next day

11h 15m • 1 change
Arrives next day

14h 50m • 1 change
Want to know about travelling from Des Moines to Mena? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Des Moines to Mena. However, there are services departing from Des Moines station and arriving at Mena station via Kansas City. The journey, including transfers, takes approximately 12h 54m.
Des Moines to Mena bus services, operated by Jefferson Lines, depart from Des Moines station.
Des Moines to Mena bus services, operated by Jefferson Lines, arrive at Mena station.
The distance between Des Moines and Mena is 782.2 km. The road distance is 913 km.
You can take a bus from Des Moines to Mena via Kansas City in around 11h 15m.