The average bus between Des Moines and Laredo takes 27h 47m and the fastest bus takes 26h 10m. The bus service runs several times per day from Des Moines to Laredo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Des Moines and Laredo. The earliest departure is at 6:30 PM in the evening, and the last departure from Des Moines is at 11:45 PM which arrives into Laredo at 5:30 AM. All services require a transfer at Kansas City Bus Station and take an average of 27h 47m. The schedules shown below are for the next available departures.
Arrives next day


26h 10m • 2 changes
Arrives +2 days


29h 45m • 2 changes
Arrives next day


26h 10m • 2 changes
Arrives +2 days


29h 45m • 2 changes
Arrives next day


26h 10m • 2 changes
Arrives +2 days


29h 45m • 2 changes
Want to know about travelling from Des Moines to Laredo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Des Moines to Laredo. However, there are services departing from Des Moines station and arriving at Laredo station via Kansas City. The journey, including transfers, takes approximately 27h 47m.
Des Moines to Laredo bus services, operated by Jefferson Lines, depart from Des Moines station.
Des Moines to Laredo bus services, operated by Jefferson Lines, arrive at Laredo Bus Station.
The distance between Des Moines and Laredo is 1,656.6 km. The road distance is 1,931 km.
You can take a bus from Des Moines to Laredo Bus Station via Kansas City Bus Station and Dallas Bus Station in around 26h 20m.