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Des Moines to Effingham buses

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Trip Overview

The average bus between Des Moines and Effingham takes 16h 18m and the fastest bus takes 16h 10m. The bus runs, on average, 6 times per week from Des Moines to Effingham. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

16h 18m
Duration
550 mi
Distance
$118
Average price
6 times a week
Frequency

Des Moines to Effingham bus times

Buses run 6 times a week between Des Moines and Effingham. The earliest departure is at 9:20 AM in the morning, and the last departure from Des Moines is at 9:45 AM which arrives into Effingham at 1:55 AM. All services require a transfer, and take on average 16h 18m. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

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    Arrives next day

    Greyhound USAGreyhound USA16h 35m • 1 change

Departing Wednesday, November 11, 2026

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    Arrives next day

    Greyhound USAGreyhound USA16h 35m • 1 change

Departing Thursday, November 12, 2026

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    Arrives next day

    Greyhound USAGreyhound USA16h 10m • 1 change

Departing Friday, November 13, 2026

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    Arrives next day

    Greyhound USAGreyhound USA16h 10m • 1 change

Departing Saturday, November 14, 2026

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    Arrives next day

    Greyhound USAGreyhound USA16h 10m • 1 change

Departing Sunday, November 15, 2026

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    Arrives next day

    Greyhound USAGreyhound USA16h 10m • 1 change

Frequently asked questions

Want to know about travelling from Des Moines to Effingham? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Des Moines to Effingham.ExpandLaunch map view
  • Distance: 550.2 mi
  • Duration: 16h 18m

What companies run services between Des Moines, IA, USA and Effingham, IL, USA?

You can take a bus from Des Moines to Effingham via Chicago Bus Station in around 11h 30m.

Operators