The average bus between Como and Pisa takes 11h 3m and the fastest bus takes 8h 55m. The bus service runs several times per day from Como to Pisa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Como and Pisa. The earliest departure is at 6:25 AM in the morning, and the last departure from Como is at 9:30 PM which arrives into Pisa at 1:20 PM. All services require a transfer, and take on average 11h 3m. The schedules shown below are for the next available departures.

10h 55m • 1 change
Arrives next day

13h • 1 change
Arrives next day

15h 50m • 1 change

10h 55m • 1 change
Arrives next day

13h • 1 change
Arrives next day

15h 50m • 1 change
Want to know about travelling from Como to Pisa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Como to Pisa. However, there are services departing from Como station and arriving at Pisa station via Milan. The journey, including transfers, takes approximately 11h 3m.
Como to Pisa bus services, operated by FlixBus, depart from Como station.
Como to Pisa bus services, operated by FlixBus, arrive at Pisa station.
Book your Como to Pisa bus tickets online with FlixBus.
The distance between Como and Pisa is 255.7 km. The road distance is 368 km.
You can take a bus from Como to Pisa via Milano, Autostazione Lampugnano in around 7h 20m.