The average bus between Comiso and Castelvetrano takes 7h 31m and the fastest bus takes 6h 5m. The bus service runs several times per day from Comiso to Castelvetrano. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Comiso and Castelvetrano. The earliest departure is at 5:55 AM in the morning, and the last departure from Comiso is at 6:15 PM which arrives into Castelvetrano at 8:05 AM. All services require a transfer at Palermo and take an average of 7h 31m. The schedules shown below are for the next available departures.

7h 5m • 1 change

6h 5m • 1 change

6h 5m • 1 change
Arrives next day

15h • 1 change

7h 5m • 1 change

6h 5m • 1 change

6h 5m • 1 change
Arrives next day

6h 50m • 1 change
Want to know about travelling from Comiso to Castelvetrano? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Comiso to Castelvetrano. However, there are services departing from Comiso station and arriving at Castelvetrano station via Palermo. The journey, including transfers, takes approximately 7h 31m.
Comiso to Castelvetrano bus services, operated by Azienda Siciliana Trasporti, depart from Comiso station.
Comiso to Castelvetrano bus services, operated by Azienda Siciliana Trasporti, arrive at Castelvetrano-V.le Roma station.
Book your Comiso to Castelvetrano bus tickets online with Azienda Siciliana Trasporti and Autoservizi Salemi Srl.
The distance between Comiso and Castelvetrano is 180 km. The road distance is 321 km.
You can take a bus from Comiso to Castelvetrano-V.le Roma via Palermo and Palermo Terminal Bus in around 6h 14m.