The average bus between Comines and Brussels takes 3h 11m and the fastest bus takes 2h 35m. The bus service runs several times per day from Comines to Brussels. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Comines and Brussels. The earliest departure is at 4:55 AM at night, and the last departure from Comines is at 11:35 PM which arrives into Brussels at 3:00 AM. All services require a transfer at Lille Europe and take an average of 3h 11m. The schedules shown below are for the next available departures.

3h 15m • 1 change

2h 55m • 1 change

3h • 1 change

3h 5m • 1 change

2h 55m • 1 change

2h 50m • 1 change

3h 15m • 1 change

2h 55m • 1 change

2h 50m • 1 change

2h 35m • 1 change

2h 45m • 1 change

2h 55m • 1 change

3h 10m • 1 change

2h 40m • 1 change

2h 45m • 1 change

3h 20m • 1 change

2h 55m • 1 change

2h 50m • 1 change

3h 15m • 1 change

2h 55m • 1 change

2h 55m • 1 change

2h 50m • 1 change

3h 15m • 1 change

2h 55m • 1 change
Want to know about travelling from Comines to Brussels? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Comines to Brussels. However, there are services departing from Comines station and arriving at Brussels station via Lille Europe. The journey, including transfers, takes approximately 3h 11m.
Comines to Brussels bus services, operated by Ilévia, depart from Comines Mairie station.
Comines to Brussels bus services, operated by Ilévia, arrive at Brussels-North train station.
The distance between Comines and Brussels is 94.8 km. The road distance is 138 km.
You can take a bus from Comines Mairie to Brussels-North train station via Lille Europe and Lille in around 3h 13m.