The average bus between Colosseum and Vatican Rome takes 29 min and the fastest bus takes 19 min. The bus runs at least 3 times per hour from Colosseum to Vatican Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 20 minutes between Colosseum and Vatican Rome. The earliest departure is at 12:02 AM at night, and the last departure from Colosseum is at 5:24 PM which arrives into Vatican Rome at 5:52 PM. All services require a transfer at Colosseo/Fori Imperiali and take an average of 29 min. The schedules shown below are for the next available departures.

19 min • 1 change

21 min • 1 change

31 min • 1 change

26 min • 1 change
Want to know about travelling from Colosseum to Vatican Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Colosseum to Vatican Rome. However, there are services departing from Colosseum station and arriving at Vatican Rome station via Argentina. The journey, including transfers, takes approximately 29 min.
Colosseum to Vatican Rome bus services, operated by ATAC S.p.A. Azienda per la mobilità, depart from Colosseo/Fori Imperiali station.
Colosseum to Vatican Rome bus services, operated by ATAC S.p.A. Azienda per la mobilità, arrive at Mazzini/Calboli station.
The distance between Colosseum and Vatican Rome is 3.8 km. The road distance is 5 km.
You can take a vehicle from Colosseum to Vatican Rome via Colosseo/Fori Imperiali, Argentina, and Mazzini/Calboli in around 32 min.