Rome2Rio

Chicago to South Side buses

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Trip Overview

The average bus between Chicago and South Side takes 11h 23m and the fastest bus takes 10h 43m. The bus service runs several times per day from Chicago to South Side. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

11h 23m
Duration
485 mi
Distance
$100
Average price
4 times a day
Frequency

Chicago to South Side bus times

Buses run 4 times a day between Chicago and South Side. The earliest departure is at 6:30 AM in the morning, and the last departure from Chicago is at 7:15 PM which arrives into South Side at 7:40 AM. All services require a transfer at Pittsburgh Intermodal Station and take an average of 11h 23m. The schedules shown below are for the next available departures.

Departing Sunday, November 15, 2026

  •  → 

    Arrives next day

    Greyhound USAPittsburgh Regional Transit10h 43m • 1 change
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    Arrives next day

    Flixbus USAPittsburgh Regional Transit11h 25m • 1 change

Departing Monday, November 16, 2026

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    Greyhound USAPittsburgh Regional Transit10h 54m • 1 change
  •  → 

    Flixbus USAPittsburgh Regional Transit13h 14m • 1 change
  •  → 

    Arrives next day

    Greyhound USAPittsburgh Regional Transit10h 43m • 1 change
  •  → 

    Arrives next day

    Flixbus USAPittsburgh Regional Transit11h 25m • 1 change

Departing Tuesday, November 17, 2026

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    Greyhound USAPittsburgh Regional Transit10h 54m • 1 change
  •  → 

    Arrives next day

    Greyhound USAPittsburgh Regional Transit10h 43m • 1 change

Departing Wednesday, November 18, 2026

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    Greyhound USAPittsburgh Regional Transit10h 54m • 1 change
  •  → 

    Arrives next day

    Greyhound USAPittsburgh Regional Transit10h 43m • 1 change
  •  → 

    Arrives next day

    Flixbus USAPittsburgh Regional Transit11h 25m • 1 change

Departing Thursday, November 19, 2026

  •  → 

    Greyhound USAPittsburgh Regional Transit10h 54m • 1 change
  •  → 

    Arrives next day

    Greyhound USAPittsburgh Regional Transit10h 43m • 1 change
  •  → 

    Arrives next day

    Flixbus USAPittsburgh Regional Transit11h 25m • 1 change

Departing Friday, November 20, 2026

  •  → 

    Greyhound USAPittsburgh Regional Transit10h 54m • 1 change
  •  → 

    Flixbus USAPittsburgh Regional Transit13h 14m • 1 change
  •  → 

    Arrives next day

    Greyhound USAPittsburgh Regional Transit11h 2m • 1 change
  •  → 

    Arrives next day

    Flixbus USAPittsburgh Regional Transit11h 33m • 1 change

Departing Saturday, November 21, 2026

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    Greyhound USAPittsburgh Regional Transit11h 3m • 1 change
  •  → 

    Flixbus USAPittsburgh Regional Transit13h 22m • 1 change

Frequently asked questions

Want to know about travelling from Chicago to South Side? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Chicago to South Side.ExpandLaunch map view
  • Distance: 484.7 mi
  • Duration: 11h 23m

What companies run services between Chicago, IL, USA and South Side, PA, USA?

Greyhound USA operates a bus from Chicago Bus Station to Pittsburgh Intermodal Station twice daily. Tickets cost $85–130 and the journey takes 10h 25m. Flixbus USA also services this route once daily.

Operators