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Chicago to Sisters buses

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Trip Overview

The bus between Chicago and Sisters takes 3d 5h. The bus runs, on average, 4 times per week from Chicago to Sisters. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3d 5h
Duration
2,538 mi
Distance
$551
Average price
4 times a week
Frequency

Chicago to Sisters bus times

Buses run 4 times a week between Chicago and Sisters. The service departs Chicago at 12:25 PM in the afternoon, which arrives into Sisters at 15:40:00. All services require a transfer at Denver Union Station and take an average of 3d 5h. The schedules shown below are for the next available departures.

Departing Friday, October 30, 2026

  •  → 

    Arrives +3 days

    Greyhound USAGreyhound USAFlixbus USAPacific Crest Buslines Bend3d 6h • 3 changes

Departing Saturday, October 31, 2026

  •  → 

    Arrives +3 days

    Greyhound USAGreyhound USAFlixbus USAPacific Crest Buslines Bend3d 6h • 3 changes

Departing Sunday, November 1, 2026

  •  → 

    Arrives +3 days

    Greyhound USAGreyhound USAFlixbus USAPacific Crest Buslines Bend3d 5h • 3 changes

Departing Monday, November 2, 2026

  •  → 

    Arrives +3 days

    Greyhound USAGreyhound USAFlixbus USAPacific Crest Buslines Bend3d 5h • 3 changes

Frequently asked questions

Want to know about travelling from Chicago to Sisters? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Chicago to Sisters.ExpandLaunch map view
  • Distance: 2,537.8 mi
  • Duration: 3d 5h

What companies run services between Chicago, IL, USA and Sisters, OR, USA?

You can take a bus from Chicago Bus Station to Sisters Mobility Hub via Denver Union Station, Pasco Bus Stop, Portland Curbside Bus Stop, and Portland Flix/Greyhound in around 2d 7h.

Operators