The average bus between Chicago and Sewickley takes 12h 19m and the fastest bus takes 12h 12m. There is at least one bus per day from Chicago to Sewickley. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Chicago and Sewickley. The earliest departure is at 6:00 PM in the evening, and the last departure from Chicago is at 7:15 PM which arrives into Sewickley at 8:27 AM. All services require a transfer at Pittsburgh Intermodal Station and take an average of 12h 19m. The schedules shown below are for the next available departures.
Arrives next day

13h 27m • 1 change
Arrives next day

13h 12m • 1 change
Arrives next day

13h 27m • 1 change
Arrives next day

13h 12m • 1 change
Want to know about travelling from Chicago to Sewickley? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Chicago to Sewickley. However, there are services departing from Chicago station and arriving at Sewickley station via Pittsburgh Intermodal Station station. The journey, including transfers, takes approximately 12h 19m.
Chicago to Sewickley bus services, operated by Flixbus USA, depart from Chicago Bus Station.
Chicago to Sewickley bus services, operated by Flixbus USA, arrive at Pittsburgh Intermodal Station.
The distance between Chicago and Sewickley is 640 km. The road distance is 798 km.
Greyhound USA operates a bus from Chicago Bus Station to Pittsburgh Intermodal Station twice daily. Tickets cost $80–160 and the journey takes 10h 25m. Flixbus USA also services this route twice daily.