The average bus between Chicago and Mena takes 24h 46m and the fastest bus takes 23h 35m. The bus service runs several times per day from Chicago to Mena. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Chicago and Mena. The earliest departure is at 6:10 AM in the morning, and the last departure from Chicago is at 12:25 PM which arrives into Mena at 2:35 PM. All services require a transfer at Des Moines and take an average of 24h 46m. The schedules shown below are for the next available departures.
Arrives next day


23h 35m • 2 changes
Arrives next day


26h 10m • 2 changes
Arrives next day


23h 35m • 2 changes
Arrives next day


26h 10m • 2 changes
Arrives next day


23h 35m • 2 changes
Arrives next day


26h 10m • 2 changes
Arrives next day


23h 35m • 2 changes
Arrives next day


26h 10m • 2 changes
Arrives next day


23h 35m • 2 changes
Arrives next day


26h 10m • 2 changes
Want to know about travelling from Chicago to Mena? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Chicago to Mena. However, there are services departing from Chicago station and arriving at Mena station via Des Moines. The journey, including transfers, takes approximately 24h 46m.
Chicago to Mena bus services, operated by Greyhound USA, depart from Chicago Bus Station.
Chicago to Mena bus services, operated by Greyhound USA, arrive at Mena station.
The distance between Chicago and Mena is 994.7 km. The road distance is 1,450 km.
You can take a bus from Chicago Bus Station to Mena via Des Moines and Kansas City in around 18h 45m.