The average bus between Chicago and Key West (Island) takes 45h 51m and the fastest bus takes 43h 30m. The bus runs, on average, 6 times per week from Chicago to Key West (Island). The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 6 times a week between Chicago and Key West (Island). The earliest departure is at 1:00 PM in the afternoon, and the last departure from Chicago is at 1:00 PM which arrives into Key West (Island) at 9:30 AM. All services require a transfer at Atlanta Bus Station and take an average of 45h 51m. The schedules shown below are for the next available departures.
Want to know about travelling from Chicago to Key West (Island)? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Chicago to Key West (Island). However, there are services departing from Chicago station and arriving at Key West (Island) station via Atlanta Bus Station station. The journey, including transfers, takes approximately 45h 51m.
Chicago to Key West (Island) bus services, operated by Flixbus USA, depart from Chicago Bus Station.
Chicago to Key West (Island) bus services, operated by Flixbus USA, arrive at Key West Airport station.
Book your Chicago to Key West (Island) bus tickets online with Flixbus USA and Greyhound USA.
The distance between Chicago and Key West (Island) is 1,999.8 km. The road distance is 2,514 km.
You can take a bus from Chicago Bus Station to Key West Airport via Atlanta Bus Station and Miami Airport Station in around 36h 5m.
