The average bus between Chicago and Holyoke takes 30h 45m and the fastest bus takes 26h 18m. The bus service runs several times per day from Chicago to Holyoke. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Chicago and Holyoke. The earliest departure is at 7:00 AM in the morning, and the last departure from Chicago is at 7:15 PM which arrives into Holyoke at 8:13 AM. All services require a transfer at Newark Penn Station and take an average of 30h 45m. The schedules shown below are for the next available departures.
Arrives next day


27h 18m • 2 changes
Arrives +2 days


34h 57m • 2 changes
Arrives next day


27h 18m • 2 changes
Arrives +2 days


34h 57m • 2 changes
Arrives next day


32h 43m • 2 changes
Arrives +2 days


34h 57m • 2 changes
Want to know about travelling from Chicago to Holyoke? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Chicago to Holyoke. However, there are services departing from Chicago station and arriving at Holyoke station via Newark Penn Station station. The journey, including transfers, takes approximately 30h 45m.
Chicago to Holyoke bus services, operated by Flixbus USA, depart from Chicago Bus Station.
Chicago to Holyoke bus services, operated by Flixbus USA, arrive at Springfield Union Station.
The distance between Chicago and Holyoke is 1,238.6 km. The road distance is 1,834 km.
You can take a bus from Chicago Bus Station to High / Hampshire via Newark Penn Station, Springfield Union Station, and Union Station Bay 9 in around 24h 41m.