The average bus between Chicago and Holyoke takes 31h 58m and the fastest bus takes 28h 47m. The bus service runs several times per day from Chicago to Holyoke. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Chicago and Holyoke. The earliest departure is at 12:25 PM in the afternoon, and the last departure from Chicago is at 7:15 PM which arrives into Holyoke at 6:12 AM. All services require a transfer at Newark Penn Station and take an average of 31h 58m. The schedules shown below are for the next available departures.
Arrives next day


28h 47m • 2 changesArrives +2 days


34h 23m • 2 changesArrives next day


28h 48m • 2 changesArrives +2 days


36h 57m • 2 changesArrives next day


29h 16m • 2 changesArrives +2 days


33h 57m • 2 changesWant to know about travelling from Chicago to Holyoke? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Chicago to Holyoke. However, there are services departing from Chicago station and arriving at Holyoke station via Newark Penn Station station. The journey, including transfers, takes approximately 31h 58m.
Chicago to Holyoke bus services, operated by Flixbus USA, depart from Chicago Bus Station.
Chicago to Holyoke bus services, operated by Flixbus USA, arrive at Springfield Union Station.
The distance between Chicago and Holyoke is 1,238.6 km. The road distance is 1,678 km.
You can take a bus from Chicago Bus Station to High / Hampshire via Newark Penn Station, Springfield Union Station, and Union Station Bay 9 in around 21h 52m.