The average bus between Chicago and Barnstable takes 34h 28m and the fastest bus takes 27h 50m. There is at least one bus per day from Chicago to Barnstable. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Chicago and Barnstable. The earliest departure is at 12:25 PM in the afternoon, and the last departure from Chicago is at 7:15 PM which arrives into Barnstable at 11:15 AM. All services require a transfer at Newark Penn Station and take an average of 34h 28m. The schedules shown below are for the next available departures.
Arrives next day



30h 50m • 3 changes
Arrives +2 days



40h • 3 changes
Arrives next day



30h 50m • 3 changes
Arrives +2 days



40h • 3 changes
Want to know about travelling from Chicago to Barnstable? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Chicago to Barnstable. However, there are services departing from Chicago station and arriving at Barnstable station via Newark Penn Station station. The journey, including transfers, takes approximately 34h 28m.
Chicago to Barnstable bus services, operated by Flixbus USA, depart from Chicago Bus Station.
Chicago to Barnstable bus services, operated by Flixbus USA, arrive at Hyannis Transportation Center station.
The distance between Chicago and Barnstable is 1,434.3 km. The road distance is 1,879 km.
You can take a bus from Chicago Bus Station to Courthouse Complex, Barnstable via Newark Penn Station, Boston, Boston South Station, and Hyannis Transportation Center in around 26h 50m.