Rome2Rio

Charlottesville to Louisville buses

Find Transport to Louisville

View schedule
QR code to download the Rome2Rio app

Download the Rome2Rio travel app

Scan QR code with your phone to download the app

Download on the App StoreGet it on Google Play

Trip Overview

The bus between Charlottesville and Louisville takes 17h 55m. The bus runs, on average, 6 times per week from Charlottesville to Louisville. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

17h 55m
Duration
725 mi
Distance
$146
Average price
6 times a week
Frequency

Charlottesville to Louisville bus times

Buses run 6 times a week between Charlottesville and Louisville. The service departs Charlottesville at 9:00 AM in the morning, which arrives into Louisville at 02:55:00. All services require a transfer at W Main St at 8th St NW and take an average of 17h 55m. The schedules shown below are for the next available departures.

Departing Monday, November 16, 2026

  •  → 

    Arrives next day

    Charlottesville Area TransitGreyhound USAAmtrak Thruway17h 55m • 2 changes

Departing Tuesday, November 17, 2026

  •  → 

    Arrives next day

    Charlottesville Area TransitGreyhound USAAmtrak Thruway17h 55m • 2 changes

Departing Wednesday, November 18, 2026

  •  → 

    Arrives next day

    Charlottesville Area TransitGreyhound USAAmtrak Thruway17h 55m • 2 changes

Departing Thursday, November 19, 2026

  •  → 

    Arrives next day

    Charlottesville Area TransitGreyhound USAAmtrak Thruway17h 55m • 2 changes

Departing Friday, November 20, 2026

  •  → 

    Arrives next day

    Charlottesville Area TransitGreyhound USAAmtrak Thruway17h 55m • 2 changes

Departing Saturday, November 21, 2026

  •  → 

    Arrives next day

    Charlottesville Area TransitGreyhound USAAmtrak Thruway17h 55m • 2 changes

Frequently asked questions

Want to know about travelling from Charlottesville to Louisville? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Charlottesville to Louisville.ExpandLaunch map view
  • Distance: 724.9 mi
  • Duration: 17h 55m

What companies run services between Charlottesville, VA, USA and Louisville, KY, USA?

You can take a bus from Downtown Transit Station to Louisville, KY via W Main St at 8th St NW, Charlottesville Union Station, and Nashville in around 17h 10m.

Operators