The average bus between Charlotte and Duke University takes 4h 15m and the fastest bus takes 3h 12m. The bus service runs several times per day from Charlotte to Duke University. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Charlotte and Duke University. The earliest departure is at 1:10 AM at night, and the last departure from Charlotte is at 11:59 PM which arrives into Duke University at 6:12 AM. All services require a transfer at Durham and take an average of 4h 15m. The schedules shown below are for the next available departures.

5h 2m • 1 change

4h 22m • 1 change

3h 12m • 1 change
Arrives next day

6h 13m • 1 change

4h 22m • 1 change

3h 12m • 1 change
Arrives next day

6h 13m • 1 change

5h 2m • 1 change

4h 22m • 1 change

3h 32m • 1 change

3h 12m • 1 change
Want to know about travelling from Charlotte to Duke University? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Charlotte to Duke University. However, there are services departing from Charlotte station and arriving at Duke University station via Durham. The journey, including transfers, takes approximately 4h 15m.
Charlotte to Duke University bus services, operated by Flixbus USA, depart from Charlotte Bus Station.
Charlotte to Duke University bus services, operated by Flixbus USA, arrive at Durham station.
The distance between Charlotte and Duke University is 192.4 km. The road distance is 234 km.
Flixbus USA operates a bus from Charlotte Bus Station to Durham 3 times a day. Tickets cost $18–35 and the journey takes 2h 36m. Greyhound USA also services this route once daily.