The average bus between Chambers St and Boston takes 5h 12m and the fastest bus takes 4h 49m. There is a bus service every few hours from Chambers St to Boston. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 2 hours between Chambers St and Boston. The earliest departure is at 12:41 AM at night, and the last departure from Chambers St is at 11:10 PM which arrives into Boston at 4:45 AM. All services require a transfer at Harrison St/Hudson St and take an average of 5h 12m. The schedules shown below are for the next available departures.

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Want to know about travelling from Chambers St to Boston? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Chambers St to Boston. However, there are services departing from Chambers St station and arriving at Boston station via Boston. The journey, including transfers, takes approximately 5h 12m.
Chambers St to Boston bus services, operated by MTA Bus Company, depart from New York Midtown station.
Chambers St to Boston bus services, operated by MTA Bus Company, arrive at Boston station.
The distance between Chambers St and Boston is 306 km. The road distance is 347 km.
Flixbus USA operates a bus from New York Midtown to Boston hourly. Tickets cost $28–50 and the journey takes 4h 20m.