The average bus between Cassino and Lecce takes 9h 36m and the fastest bus takes 8h 20m. The bus service runs several times per day from Cassino to Lecce. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Cassino and Lecce. The earliest departure is at 9:45 AM in the morning, and the last departure from Cassino is at 8:30 PM which arrives into Lecce at 6:45 AM. All services require a transfer, and take on average 9h 36m. The schedules shown below are for the next available departures.

8h 20m • 1 change

8h 30m • 1 change
Arrives next day

10h 15m • 1 change

8h 20m • 1 change

11h 55m • 1 change
Arrives next day

10h 15m • 1 change

8h 20m • 1 change
Arrives next day

13h 20m • 1 change
Arrives next day

11h 40m • 1 change

8h 20m • 1 change

8h 30m • 1 change
Arrives next day

12h 30m • 1 change
Want to know about travelling from Cassino to Lecce? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Cassino to Lecce. However, there are services departing from Cassino station and arriving at Lecce station via Napoli P.zza Garibaldi. The journey, including transfers, takes approximately 9h 36m.
Cassino to Lecce bus services, operated by FlixBus, depart from Cassino station.
Cassino to Lecce bus services, operated by FlixBus, arrive at Lecce station.
Book your Cassino to Lecce bus tickets online with FlixBus.
The distance between Cassino and Lecce is 386 km. The road distance is 493 km.
You can take a bus from Cassino to Lecce via Napoli P.zza Garibaldi in around 8h.