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Cary to Key West buses

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Trip Overview

The average bus between Cary and Key West takes 45h 12m and the fastest bus takes 41h 17m. The bus runs, on average, 3 times per week from Cary to Key West. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

45h 12m
Duration
1,326 mi
Distance
$262
Average price
3 times a week
Frequency

Cary to Key West bus times

Buses run 3 times a week between Cary and Key West. The earliest departure is at 8:00 AM in the morning, and the last departure from Cary is at 7:45 PM which arrives into Key West at 1:02 PM. All services require a transfer at Regional Transit Center and take an average of 45h 12m. The schedules shown below are for the next available departures.

Departing Monday, November 2, 2026

  •  → 

    Arrives +2 days

    Go TriangleGo TriangleFlixbus USAFlixbus USAGreyhound USAKey West Transit41h 17m • 5 changes

Departing Tuesday, November 3, 2026

  •  → 

    Arrives +2 days

    Go TriangleGo TriangleGreyhound USAFlixbus USAGreyhound USAKey West Transit2d 5h • 5 changes

Departing Friday, November 6, 2026

  •  → 

    Arrives +2 days

    Go TriangleGo TriangleFlixbus USAFlixbus USAGreyhound USAKey West Transit41h 17m • 5 changes

Frequently asked questions

Want to know about travelling from Cary to Key West? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Cary to Key West.ExpandLaunch map view
  • Distance: 1,325.8 mi
  • Duration: 45h 12m

What companies run services between Cary, NC, USA and Key West, FL, USA?

You can take a bus from Cary Depot to N Roosevelt & 3rd Street via Regional Transit Center, Durham Station, Durham, Richmond, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 32h 40m.

Operators