The average bus between Cape Cod and South Boston takes 3h 27m and the fastest bus takes 2h 16m. The bus service runs several times per day from Cape Cod to South Boston. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 2 hours between Cape Cod and South Boston. The earliest departure is at 6:34 AM in the morning, and the last departure from Cape Cod is at 8:46 PM which arrives into South Boston at 5:50 AM. All services require a transfer, and take on average 3h 27m. The schedules shown below are for the next available departures.

2h 34m • 1 change

2h 54m • 1 change

4h 4m • 1 change
Arrives next day

9h 4m • 1 change

2h 16m • 1 change

3h 16m • 1 change

3h 4m • 1 change

3h 4m • 1 change

2h 16m • 1 change

3h 16m • 1 change

3h 4m • 1 change

3h 4m • 1 change

3h 4m • 1 change

3h 4m • 1 change

3h 4m • 1 change

3h 4m • 1 change

2h 16m • 1 change

3h 16m • 1 change

3h 4m • 1 change

3h 4m • 1 change
Want to know about travelling from Cape Cod to South Boston? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Cape Cod to South Boston. However, there are services departing from Cape Cod station and arriving at South Boston station via Boston South Buses. The journey, including transfers, takes approximately 3h 27m.
Cape Cod to South Boston bus services, operated by Cape Cod Regional Transit Authority, depart from Hyannis Transportation Center station.
Cape Cod to South Boston bus services, operated by Cape Cod Regional Transit Authority, arrive at Boston South Buses station.
The distance between Cape Cod and South Boston is 101 km. The road distance is 126 km.
Plymouth & Brockton operates a bus from Hyannis Transportation Center to Boston South Buses hourly. Tickets cost $27–35 and the journey takes 1h 50m.