The average bus between Cape Cod and Portland takes 6h 9m and the fastest bus takes 5h 21m. The bus service runs several times per day from Cape Cod to Portland. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 2 hours between Cape Cod and Portland. The earliest departure is at 6:34 AM in the morning, and the last departure from Cape Cod is at 8:46 PM which arrives into Portland at 9:55 AM. All services require a transfer at Hyannis Transportation Center and take an average of 6h 9m. The schedules shown below are for the next available departures.


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5h 36m • 2 changes


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5h 24m • 2 changes


5h 21m • 2 changes


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Want to know about travelling from Cape Cod to Portland? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Cape Cod to Portland. However, there are services departing from Cape Cod station and arriving at Portland station via Boston South Buses. The journey, including transfers, takes approximately 6h 9m.
Cape Cod to Portland bus services, operated by Cape Cod Regional Transit Authority, depart from Hyannis Transportation Center station.
Cape Cod to Portland bus services, operated by Cape Cod Regional Transit Authority, arrive at Portland, ME station.
The distance between Cape Cod and Portland is 219.9 km. The road distance is 296 km.
You can take a bus from Town Hall Lawton Bus Shelter to Portland, ME via Hyannis Transportation Center, Boston, Bus Terminal South Station, and Boston, MA - South Station in around 5h 3m.