The average bus between Canonsburg and Chicago takes 14h 13m and the fastest bus takes 13h 37m. The bus service runs several times per day from Canonsburg to Chicago. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Canonsburg and Chicago. The earliest departure is at 5:34 AM in the morning, and the last departure from Canonsburg is at 5:15 PM which arrives into Chicago at 6:10 AM. All services require a transfer at East Busway - near Amtrak/Greyhound and take an average of 14h 13m. The schedules shown below are for the next available departures.

13h 20m • 1 change

12h 37m • 1 change
Arrives next day

12h 54m • 1 change

13h 20m • 1 change

12h 37m • 1 change
Arrives next day

12h 54m • 1 change
Want to know about travelling from Canonsburg to Chicago? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Canonsburg to Chicago. However, there are services departing from Canonsburg station and arriving at Chicago station via Chicago Bus Station station. The journey, including transfers, takes approximately 14h 13m.
Canonsburg to Chicago bus services, operated by Freedom Transit, depart from Pittsburgh Intermodal Station.
Canonsburg to Chicago bus services, operated by Freedom Transit, arrive at Chicago Bus Station.
The distance between Canonsburg and Chicago is 648.8 km. The road distance is 800 km.
Greyhound USA operates a bus from Pittsburgh Intermodal Station to Chicago Bus Station twice daily. Tickets cost $70–140 and the journey takes 10h 5m. Flixbus USA also services this route once daily.