The average bus between Calais and Siena takes 24h 39m and the fastest bus takes 24h 15m. There is at least one bus per day from Calais to Siena. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Calais and Siena. The earliest departure is at 2:05 PM in the afternoon, and the last departure from Calais is at 5:40 PM which arrives into Siena at 6:55 PM. All services require a transfer at Paris, Quai de Bercy (Bercy Seine) and take an average of 24h 39m. The schedules shown below are for the next available departures.
Arrives next day


24h 15m • 2 changes
Arrives next day


25h 15m • 2 changes
Arrives next day


24h 15m • 2 changes
Arrives next day


25h 15m • 2 changes
Want to know about travelling from Calais to Siena? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Calais to Siena. However, there are services departing from Calais station and arriving at Siena station via Paris, Quai de Bercy (Bercy Seine). The journey, including transfers, takes approximately 24h 39m.
Calais to Siena bus services, operated by FlixBus, depart from Calais station.
Calais to Siena bus services, operated by FlixBus, arrive at Siena station.
Book your Calais to Siena bus tickets online with FlixBus and BlaBlaCar Bus.
The distance between Calais and Siena is 1,109.1 km. The road distance is 1,557 km.
You can take a bus from Calais to Siena via Paris, Quai de Bercy (Bercy Seine), Paris - Bercy-Seine Bus Station, and Florence Villa Constanza Bus Station in around 22h 51m.