The average bus between Calais and Avignon takes 13h 17m and the fastest bus takes 12h 20m. The bus service runs several times per day from Calais to Avignon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Calais and Avignon. The earliest departure is at 2:55 AM at night, and the last departure from Calais is at 6:30 PM which arrives into Avignon at 6:50 AM. All services require a transfer, and take on average 13h 17m. The schedules shown below are for the next available departures.

13h 15m • 1 change
Arrives next day

14h • 1 change
Arrives next day

13h 15m • 1 change
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13h 10m • 1 change

13h • 1 change
Arrives next day

14h • 1 change
Arrives next day

13h 15m • 1 change
Arrives next day

13h 10m • 1 change

13h • 1 change
Arrives next day

14h • 1 change
Arrives next day

13h 15m • 1 change
Arrives next day

12h 20m • 1 change
Want to know about travelling from Calais to Avignon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Calais to Avignon. However, there are services departing from Calais station and arriving at Avignon station via Paris, Quai de Bercy (Bercy Seine). The journey, including transfers, takes approximately 13h 17m.
Calais to Avignon bus services, operated by FlixBus, depart from Calais station.
Calais to Avignon bus services, operated by FlixBus, arrive at Avignon station.
Book your Calais to Avignon bus tickets online with FlixBus.
The distance between Calais and Avignon is 809.6 km. The road distance is 976 km.
You can take a bus from Calais to Avignon via Paris, Quai de Bercy (Bercy Seine) in around 12h 50m.