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Buffalo to Midtown Manhattan buses

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Trip Overview

The average bus between Buffalo and Midtown Manhattan takes 8h 35m and the fastest bus takes 8h 5m. There is a bus service every few hours from Buffalo to Midtown Manhattan. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

8h 35m
Duration
422 mi
Distance
$240
Average price
Hourly
Frequency

Buffalo to Midtown Manhattan bus times

Buses run hourly between Buffalo and Midtown Manhattan. The earliest departure is at 12:55 AM at night, and the last departure from Buffalo is at 11:00 PM which arrives into Midtown Manhattan at 7:35 AM. All services run direct with no transfers required, and take on average 8h 35m. The schedules shown below are for the next available departures.

Departing Saturday, November 14, 2026

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    Arrives next day

    bus bus 8h 35m • Direct
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    Arrives next day

    bus bus 8h 35m • Direct

Departing Sunday, November 15, 2026

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    bus bus 8h 15m • Direct
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    bus bus 8h 45m • Direct
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    bus bus 8h 40m • Direct
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    bus bus 8h 30m • Direct
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Departing Monday, November 16, 2026

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    bus bus 8h 15m • Direct
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    bus bus 8h 45m • Direct
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    bus bus 8h 40m • Direct
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    bus bus 8h 30m • Direct
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Departing Tuesday, November 17, 2026

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    bus bus 8h 15m • Direct
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    bus bus 8h 45m • Direct
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    bus bus 8h 40m • Direct
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    bus bus 8h 30m • Direct
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Departing Wednesday, November 18, 2026

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    bus bus 8h 15m • Direct
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    bus bus 8h 45m • Direct
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    bus bus 8h 30m • Direct
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    bus bus 8h 45m • Direct
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Departing Thursday, November 19, 2026

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    bus bus 8h 15m • Direct
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    bus bus 8h 30m • Direct
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    bus bus 8h 45m • Direct
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    bus bus 8h 50m • Direct
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Departing Friday, November 20, 2026

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    bus bus 8h 15m • Direct
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    bus bus 8h 40m • Direct
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    bus bus 8h 30m • Direct
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    bus bus 8h 45m • Direct
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Frequently asked questions

Want to know about travelling from Buffalo to Midtown Manhattan? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Buffalo to Midtown Manhattan.ExpandLaunch map view
  • Distance: 422 mi
  • Duration: 8h 35m

What companies run services between Buffalo, NY, USA and Midtown Manhattan, NY, USA?

Flixbus USA operates a bus from Buffalo to New York Midtown every 4 hours. Tickets cost $65–100 and the journey takes 8h 25m. Two other operators also service this route.

Operators