The average bus between Buffalo and Harlem takes 9h 35m and the fastest bus takes 9h 6m. The bus service runs several times per day from Buffalo to Harlem. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Buffalo and Harlem. The earliest departure is at 3:30 AM at night, and the last departure from Buffalo is at 11:59 PM which arrives into Harlem at 9:36 AM. All services require a transfer at New York Midtown and take an average of 9h 35m. The schedules shown below are for the next available departures.

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Want to know about travelling from Buffalo to Harlem? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Buffalo to Harlem. However, there are services departing from Buffalo station and arriving at Harlem station via New York Midtown. The journey, including transfers, takes approximately 9h 35m.
Buffalo to Harlem bus services, operated by Flixbus USA, depart from Buffalo station.
Buffalo to Harlem bus services, operated by Flixbus USA, arrive at New York Midtown station.
The distance between Buffalo and Harlem is 469.3 km. The road distance is 688 km.
Flixbus USA operates a bus from Buffalo to New York Midtown every 3 hours. Tickets cost $50–90 and the journey takes 8h 25m.