The average bus between Buffalo and Harlem takes 9h 3m and the fastest bus takes 8h 22m. The bus service runs several times per day from Buffalo to Harlem. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Buffalo and Harlem. The earliest departure is at 6:00 AM in the morning, and the last departure from Buffalo is at 11:15 PM which arrives into Harlem at 7:52 AM. All services require a transfer, and take on average 9h 3m. The schedules shown below are for the next available departures.

9h 15m • 1 change
9h 26m • 1 changeArrives next day

8h 22m • 1 change
9h 11m • 1 change
9h 14m • 1 changeArrives next day

8h 30m • 1 change
9h 9m • 1 change
9h 10m • 1 changeArrives next day

8h 37m • 1 changeWant to know about travelling from Buffalo to Harlem? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Buffalo to Harlem. However, there are services departing from Buffalo station and arriving at Harlem station via New York. The journey, including transfers, takes approximately 9h 3m.
Buffalo to Harlem bus services, operated by Trailways, depart from Buffalo station.
Buffalo to Harlem bus services, operated by Trailways, arrive at New York station.
The distance between Buffalo and Harlem is 469.3 km. The road distance is 746 km.
Trailways operates a bus from Buffalo to New York every 4 hours. Tickets cost $60–280 and the journey takes 7h 55m.