The bus between Buffalo and Des Moines takes 27h 40m. The bus runs, on average, 6 times per week from Buffalo to Des Moines. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 6 times a week between Buffalo and Des Moines. The earliest departure is at 11:55 AM in the morning, and the last departure from Buffalo is at 11:55 AM which arrives into Des Moines at 3:35 PM. All services require a transfer at Cleveland Bus Station and take an average of 27h 40m. The schedules shown below are for the next available departures.
Want to know about travelling from Buffalo to Des Moines? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Buffalo to Des Moines. However, there are services departing from Buffalo station and arriving at Des Moines station via Cleveland Bus Station station. The journey, including transfers, takes approximately 27h 40m.
Buffalo to Des Moines bus services, operated by Jefferson Lines, depart from Buffalo station.
Buffalo to Des Moines bus services, operated by Jefferson Lines, arrive at Des Moines station.
Book your Buffalo to Des Moines bus tickets online with Jefferson Lines.
The distance between Buffalo and Des Moines is 1,219.4 km. The road distance is 1,430 km.
You can take a bus from Buffalo to Des Moines via Cleveland Bus Station and Chicago in around 20h 15m.
