The average bus between Brussels and Messina takes 38h 22m and the fastest bus takes 33h 40m. There is at least one bus per day from Brussels to Messina. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Brussels and Messina. The earliest departure is at 8:40 PM in the evening, and the last departure from Brussels is at 11:35 PM which arrives into Messina at 7:50 PM. All services require a transfer, and take on average 38h 22m. The schedules shown below are for the next available departures.
Arrives +2 days

33h 40m • 1 change
Arrives +2 days

44h 15m • 1 change
Arrives +2 days

33h 40m • 1 change
Arrives +2 days

44h 15m • 1 change
Arrives +2 days

33h 40m • 1 change
Arrives +2 days

44h 15m • 1 change
Want to know about travelling from Brussels to Messina? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Brussels to Messina. However, there are services departing from Brussels station and arriving at Messina station via Milano, Autostazione Lampugnano. The journey, including transfers, takes approximately 38h 22m.
Brussels to Messina bus services, operated by BlaBlaCar Bus, depart from Brussels - Midi Train Station.
Brussels to Messina bus services, operated by BlaBlaCar Bus, arrive at Messina station.
Book your Brussels to Messina bus tickets online with BlaBlaCar Bus and FlixBus.
The distance between Brussels and Messina is 1,660.1 km. The road distance is 2,195 km.
You can take a bus from Brussels - Midi Train Station to Messina via Milano, Autostazione Lampugnano in around 31h 5m.