The average bus between Brussels and Desio takes 16h 44m and the fastest bus takes 14h 14m. There is at least one bus per day from Brussels to Desio. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Brussels and Desio. The earliest departure is at 4:00 PM in the afternoon, and the last departure from Brussels is at 8:00 PM which arrives into Desio at 6:38 AM. All services require a transfer at Milan and take an average of 16h 44m. The schedules shown below are for the next available departures.
Arrives next day


16h 14m • 2 changes
Arrives next day


16h 22m • 2 changes
Arrives next day


16h 25m • 2 changes
Arrives next day


16h 24m • 2 changes
Want to know about travelling from Brussels to Desio? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Brussels to Desio. However, there are services departing from Brussels station and arriving at Desio station via Milan. The journey, including transfers, takes approximately 16h 44m.
Brussels to Desio bus services, operated by FlixBus, depart from Brussels-North train station.
Brussels to Desio bus services, operated by FlixBus, arrive at Milan station.
The distance between Brussels and Desio is 683.5 km. The road distance is 891 km.
FlixBus operates a bus from Brussels-North train station to Milan once daily. Tickets cost €60–110 and the journey takes 12h 25m.