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Brookline to Chicago buses

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Trip Overview

The average bus between Brookline and Chicago takes 26h 42m and the fastest bus takes 21h 43m. The bus service runs several times per day from Brookline to Chicago. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

26h 42m
Duration
1,088 mi
Distance
$184
Average price
Twice daily
Frequency

Bus

best
  1. Take the bus from Boston to Newark Penn Stationbus bus Greyhound US0235 / ...
  2. Take the bus from Newark Penn Station to Chicago Bus Stationbus bus FlixBus N2641 / ...
23h 30m
$142–279

Brookline to Chicago bus times

Buses run twice daily between Brookline and Chicago. The earliest departure is at 12:17 AM at night, and the last departure from Brookline is at 4:42 PM which arrives into Chicago at 1:25 PM. All services require a transfer at Essex St @ Atlantic Ave and take an average of 26h 42m. The schedules shown below are for the next available departures.

Frequently asked questions

Want to know about travelling from Brookline to Chicago? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Brookline to Chicago.ExpandLaunch map view
  • Distance: 1,088.1 mi
  • Duration: 26h 42m

What companies run services between Brookline, MA, USA and Chicago, IL, USA?

You can take a bus from Nubian to Chicago Bus Station via Essex St @ Atlantic Ave, Boston, and Newark Penn Station in around 23h 30m.

Operators

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Bus trips from Brookline

Bus trips to Chicago

Alternative transport options