The average bus between Brighton and Slough takes 2h 28m and the fastest bus takes 2h 14m. There is a bus service every few hours from Brighton to Slough. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Brighton and Slough. The earliest departure is at 2:35 AM at night, and the last departure from Brighton is at 11:20 PM which arrives into Slough at 1:51 AM. All services require a transfer, and take on average 2h 28m. The schedules shown below are for the next available departures.

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2h 52m • 1 changeWant to know about travelling from Brighton to Slough? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Brighton to Slough. However, there are services departing from Preston Circus station and arriving at Heathrow Terminal 5 station via Heathrow Terminal 5 station. The journey, including transfers, takes approximately 2h 28m.
Brighton to Slough bus services, operated by National Express, depart from Preston Circus station.
Brighton to Slough bus services, operated by National Express, arrive at Heathrow Terminal 5 station.
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The distance between Brighton and Slough is 82.1 km. The road distance is 107 km.
National Express operates a bus from Preston Circus to Heathrow Terminal 5 hourly. Tickets cost £10–17 and the journey takes 1h 53m.