The average bus between Boston and East Harlem takes 5h 10m and the fastest bus takes 4h 40m. There is a bus service every few hours from Boston to East Harlem. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Boston and East Harlem. The earliest departure is at 1:00 AM at night, and the last departure from Boston is at 10:00 PM which arrives into East Harlem at 3:22 AM. All services require a transfer at New York Midtown and take an average of 5h 10m. The schedules shown below are for the next available departures.

5h 2m • 1 change

5h 21m • 1 change

5h 36m • 1 change

5h 9m • 1 change

5h 2m • 1 change

5h 21m • 1 change

5h 39m • 1 change

5h 36m • 1 change

5h 2m • 1 change

5h 21m • 1 change

5h 39m • 1 change

5h 36m • 1 change

4h 59m • 1 change

5h 7m • 1 change

5h 23m • 1 change

5h 18m • 1 change
Want to know about travelling from Boston to East Harlem? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Boston to East Harlem. However, there are services departing from Boston station and arriving at East Harlem station via New York Midtown. The journey, including transfers, takes approximately 5h 10m.
Boston to East Harlem bus services, operated by Flixbus USA, depart from Boston station.
Boston to East Harlem bus services, operated by Flixbus USA, arrive at New York Midtown station.
The distance between Boston and East Harlem is 296.2 km. The road distance is 348 km.
Flixbus USA operates a bus from Boston to New York Midtown hourly. Tickets cost $27–50 and the journey takes 4h 20m.