The average bus between Blythe and Santa Ana takes 8h 20m and the fastest bus takes 5h 38m. The bus service runs several times per day from Blythe to Santa Ana. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Blythe and Santa Ana. The earliest departure is at 2:45 AM at night, and the last departure from Blythe is at 7:40 PM which arrives into Santa Ana at 6:11 AM. All services require a transfer at San Bernardino, CA and take an average of 8h 20m. The schedules shown below are for the next available departures.
Arrives next day


23h 51m • 2 changes
Arrives next day


10h 31m • 2 changes


6h 24m • 2 changes


5h 51m • 2 changes
Arrives next day


10h 31m • 2 changes
Want to know about travelling from Blythe to Santa Ana? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Blythe to Santa Ana. However, there are services departing from Blythe station and arriving at Santa Ana station via San Bernardino, CA. The journey, including transfers, takes approximately 8h 20m.
Blythe to Santa Ana bus services, operated by CBX Cross Border Express, depart from Blythe McDonalds station.
Blythe to Santa Ana bus services, operated by CBX Cross Border Express, arrive at Harbor + Katella station.
Book your Blythe to Santa Ana bus tickets online with CBX Cross Border Express, Riverside Transit Agency and 2 other operators.
The distance between Blythe and Santa Ana is 303.1 km. The road distance is 368 km.
You can take a bus from Blythe McDonalds to Main-Civic Center via San Bernardino, CA, San Bernardino, Harbor + Katella, and Katella-Harbor in around 5h 52m.