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Bethesda to St. Louis buses

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Trip Overview

The average bus between Bethesda and St. Louis takes 22h 52m and the fastest bus takes 22h 47m. The bus runs, on average, 4 times per week from Bethesda to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

22h 52m
Duration
925 mi
Distance
$195
Average price
4 times a week
Frequency

Bethesda to St. Louis bus times

Buses run 4 times a week between Bethesda and St. Louis. The earliest departure is at 10:12 AM in the morning, and the last departure from Bethesda is at 10:27 AM which arrives into St. Louis at 8:15 AM. All services require a transfer at Massachusetts Av NE+1 St NE and take an average of 22h 52m. The schedules shown below are for the next available departures.

Departing Sunday, November 15, 2026

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    Arrives next day

    Washington Metropolitan Area Transit AuthorityGreyhound USAGreyhound USA23h 2m • 2 changes

Departing Thursday, November 19, 2026

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    Arrives next day

    Washington Metropolitan Area Transit AuthorityGreyhound USAGreyhound USA22h 47m • 2 changes

Departing Friday, November 20, 2026

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    Arrives next day

    Washington Metropolitan Area Transit AuthorityGreyhound USAGreyhound USA22h 47m • 2 changes

Departing Saturday, November 21, 2026

  •  → 

    Arrives next day

    Washington Metropolitan Area Transit AuthorityGreyhound USAGreyhound USA22h 52m • 2 changes

Frequently asked questions

Want to know about travelling from Bethesda to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Bethesda to St. Louis.ExpandLaunch map view
  • Distance: 924.6 mi
  • Duration: 22h 52m

What companies run services between Bethesda, MD, USA and St. Louis, MO, USA?

You can take a bus from Wisconsin Av NW+Albemarle St NW to St Louis Bus Station via Massachusetts Av NE+1 St NE, Washington Union Station, and Harrisburg Bus Station in around 23h 42m.

Operators