The average bus between Berlin and Mainhausen takes 10h 22m and the fastest bus takes 9h 39m. The bus service runs several times per day from Berlin to Mainhausen. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Berlin and Mainhausen. The earliest departure is at 2:20 AM at night, and the last departure from Berlin is at 8:40 PM which arrives into Mainhausen at 7:59 AM. All services require a transfer at Frankfurt Airport and take an average of 10h 22m. The schedules shown below are for the next available departures.


9h 39m • 2 changes


10h 49m • 2 changes
Arrives next day


10h 19m • 2 changes


9h 39m • 2 changes


10h 49m • 2 changes
Arrives next day


10h 19m • 2 changes


9h 39m • 2 changes


10h 49m • 2 changes
Arrives next day


11h 32m • 2 changes


9h 52m • 2 changes


10h 49m • 2 changes
Arrives next day


10h 19m • 2 changes
Want to know about travelling from Berlin to Mainhausen? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Berlin to Mainhausen. However, there are services departing from Berlin station and arriving at Mainhausen station via Frankfurt Airport. The journey, including transfers, takes approximately 10h 22m.
Berlin to Mainhausen bus services, operated by FlixBus, depart from Berlin, Zentralen Omnibusbahnhof station.
Berlin to Mainhausen bus services, operated by FlixBus, arrive at Frankfurt Airport station.
The distance between Berlin and Mainhausen is 415.3 km. The road distance is 572 km.
FlixBus operates a bus from Berlin, Zentralen Omnibusbahnhof to Frankfurt Airport 3 times a day. Tickets cost €35–65 and the journey takes 7h 25m.