The average bus between Ayr and London takes 12h 17m and the fastest bus takes 10h 40m. The bus service runs several times per day from Ayr to London. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Ayr and London. The earliest departure is at 7:05 AM in the morning, and the last departure from Ayr is at 11:40 PM which arrives into London at 8:10 PM. All services require a transfer, and take on average 12h 17m. The schedules shown below are for the next available departures.

13h 5m • 1 change
13h 40m • 1 changeArrives next day

10h 40m • 1 changeArrives next day

10h 40m • 1 changeWant to know about travelling from Ayr to London? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Ayr to London. However, there are services departing from Ayr Bus Station and arriving at London Victoria Coach Station Arrivals via Buchanan Bus Station. The journey, including transfers, takes approximately 12h 17m.
Ayr to London bus services, operated by Stagecoach West Scotland, depart from Ayr Bus Station.
Ayr to London bus services, operated by National Express, arrive at London Victoria Coach Station Arrivals.
The distance between Ayr and London is 531.1 km. The road distance is 630 km.
You can take a bus from Ayr Bus Station to London Victoria Coach Station Arrivals via Buchanan Bus Station in around 10h 42m.