The average bus between Ayr and Hamilton takes 1h 55m and the fastest bus takes 1h 34m. There is a bus service every few hours from Ayr to Hamilton. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Ayr and Hamilton. The earliest departure is at 6:00 AM in the morning, and the last departure from Ayr is at 5:40 PM which arrives into Hamilton at 8:09 PM. All services require a transfer, and take on average 1h 55m. The schedules shown below are for the next available departures.

1h 49m • 1 change

1h 44m • 1 change

1h 59m • 1 change

1h 59m • 1 change

1h 49m • 1 change

1h 44m • 1 change

1h 59m • 1 change

1h 59m • 1 change

1h 49m • 1 change

1h 44m • 1 change

1h 59m • 1 change

1h 59m • 1 change
Want to know about travelling from Ayr to Hamilton? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Ayr to Hamilton. However, there are services departing from Ayr station and arriving at Hamilton station via Buchanan Bus Station station. The journey, including transfers, takes approximately 1h 55m.
Ayr to Hamilton bus services, operated by Stagecoach West Scotland, depart from Ayr Bus Station.
Ayr to Hamilton bus services, operated by Stagecoach West Scotland, arrive at Portland Park station.
The distance between Ayr and Hamilton is 50.6 km. The road distance is 80 km.
You can take a bus from Ayr Bus Station to Portland Park via Buchanan Bus Station in around 1h 43m.