The average bus between Avignon and Les Issambres takes 6h 20m and the fastest bus takes 4h. The bus service runs several times per day from Avignon to Les Issambres. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Avignon and Les Issambres. The earliest departure is at 6:34 AM in the morning, and the last departure from Avignon is at 7:00 PM which arrives into Les Issambres at 6:41 AM. All services require a transfer at Gare Routière and take an average of 6h 20m. The schedules shown below are for the next available departures.



4h 29m • 3 changes


5h 30m • 3 changes


4h 18m • 3 changes


6h • 3 changesWant to know about travelling from Avignon to Les Issambres? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Avignon to Les Issambres. However, there are services departing from Avignon station and arriving at Les Issambres station via Gare Routière. The journey, including transfers, takes approximately 6h 20m.
Avignon to Les Issambres bus services, operated by Zou! Lignes Express Régionales, depart from Limbert/Remparts station.
Avignon to Les Issambres bus services, operated by Zou! Lignes Express Régionales, arrive at Gare Routière station.
The distance between Avignon and Les Issambres is 167.1 km. The road distance is 238 km.
You can take a bus from Limbert/Remparts to Touring Club via Gare Routière, Fréjus Gare Routière, and Gare Routière in around 5h 30m.