The average bus between Antwerp and Santander takes 20h 15m and the fastest bus takes 18h 35m. The bus service runs several times per day from Antwerp to Santander. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Antwerp and Santander. The earliest departure is at 9:10 AM in the morning, and the last departure from Antwerp is at 7:40 PM which arrives into Santander at 5:25 PM. All services require a transfer at Brussels-North train station and take an average of 20h 15m. The schedules shown below are for the next available departures.
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18h 35m • 2 changesArrives next day


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23h 35m • 2 changesWant to know about travelling from Antwerp to Santander? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Antwerp to Santander. However, there are services departing from Antwerp station and arriving at Santander station via Brussels-North train station station. The journey, including transfers, takes approximately 20h 15m.
Antwerp to Santander bus services, operated by FlixBus, depart from Antwerp Rooseveltplaats station.
Antwerp to Santander bus services, operated by FlixBus, arrive at Estación de autobuses de Santander station.
Book your Antwerp to Santander bus tickets online with FlixBus and ALSA.
The distance between Antwerp and Santander is 1,059.7 km. The road distance is 1,388 km.
You can take a bus from Antwerp Rooseveltplaats to Estación de autobuses de Santander via Brussels-North train station, Bilbao, and Bilbao Intermodal in around 22h 30m.