The average bus between Afyon and Istanbul takes 8h 43m and the fastest bus takes 7h. The bus service runs several times per day from Afyon to Istanbul. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Afyon and Istanbul. The earliest departure is at 2:30 AM at night, and the last departure from Afyon is at 11:45 PM which arrives into Istanbul at 6:45 AM. All services require a transfer, and take on average 8h 43m. The schedules shown below are for the next available departures.

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10h 15m • 1 changeWant to know about travelling from Afyon to Istanbul? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Afyon to Istanbul. However, there are services departing from Afyon station and arriving at Istanbul station via Sakarya bus station station. The journey, including transfers, takes approximately 8h 43m.
Afyon to Istanbul bus services, operated by Kamil Koç, depart from Afyon bus station.
Afyon to Istanbul bus services, operated by Kamil Koç, arrive at İstanbul Esenler bus station.
Book your Afyon to Istanbul bus tickets online with Kamil Koç, Kale Seyahat and Mersin Turizm.
The distance between Afyon and Istanbul is 280.8 km. The road distance is 465 km.
You can take a bus from Afyon bus station to İstanbul Esenler bus station via Sakarya bus station in around 8h 6m.