From Split line 38 bus to Split airport, fly to Frankfurt airport, light rail to Hauptwache, then Subway to Frankfurt am Main. 5hrs 49min 173 €. From Split train to Zagreb Glavni Kolod. then train to Frankfurt(Main)Hbf. 20hrs 01min 178 €. From Split bus to Frankfurt Hbf. 22hrs 15min 101 €. From Split drive to Frankfurt am Main. 13hrs 28min 217 €.