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From Santander airport fly to Barcelona airport then Train to Barcelona. 1hrs 40min $105. From Santander bus to Termibús, bus to Bilbao airport, fly to Barcelona airport, then Train to Barcelona. 6hrs 00min $99. From Santander bus to Bilbao, bus to Vitoria/Gasteiz, train to Zaragoza Delicias, then train to Barcelona Sants. 8hrs 22min $85. From Santander bus to Barcelona Sants. 9hrs 52min $53. From Santander bus to Pamplona then bus to Barcelona. 10hrs 20min $55. From Santander rideshare to Barcelone. 8hrs 13min $45. From Santander drive to Barcelona. 7hrs 15min $123.

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