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From Roma Termini train to Genova Piazza Principe then train to Savona. 5hrs 21min 76 €. From Ara Coeli- Piazza Venezia line 492 bus to Rome, Bus to De Ferrari, bus to Genova Piazza Principe, then train to Savona. 9hrs 23min. From Rome drive to Savona. 5hrs 50min 97 €. From Roma Termini train to Rome airport, fly to Genoa airport, then train to Savona. 3hrs 31min 148 €.