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From Roma Termini train to Genova Piazza Principe then train to Savona. 5hrs 50min 78 €. From Cavour Metro to Rome, bus to Siena, bus to Pisa, line 10 bus to Livorno, then bus to Savona. 11hrs 37min. From Rome drive to Savona. 5hrs 53min 93 €. From Roma Termini train to Rome airport, fly to Genoa airport, then train to Savona. 3hrs 31min 142 €. From Roma Termini train to Rome airport, fly to Nice airport, train to Ventimiglia, then train to Savona. 7hrs 25min 145 €.