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From Roma Termini train to Genova Piazza Principe then train to Savona. 5hrs 20min 75 €. From Cavour- Ricci bus to Rome, bus to Siena, bus to De Ferrari, bus to Genova Piazza Principe, then train to Savona. 9hrs 28min. From Rome drive to Savona. 5hrs 50min 101 €. From Roma Termini train to Rome airport, fly to Genoa airport, then train to Savona. 3hrs 33min 113 €.