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From Roma Termini train to Napoli Centrale, train to Villa San Giovanni, then ferry to Messina Marittima. 6hrs 24min 92 €. From Roma Ostiense train to Messina Centrale. 9hrs 29min 94 €. From Rome bus to Messina. 9hrs 33min 47 €. From Cavour Metro to Rome, bus to Villa San Giovanni, then ferry to Rada San Francesco. 9hrs 58min 43 €. From Roma Termini train to Rome airport, fly to Reggio Calabria airport, bus to Reggio di Calabria, then ferry to Messina. 6hrs 10min 81 €. From Roma Termini train to Rome airport, fly to Catania airport, bus to Catania Centrale, then train to Messina. 6hrs 46min 97 €. From Roma Termini train to Rome airport, fly to Palermo airport, train to Palermo Centrale, then train to Messina. 8hrs 57min 110 €. From Roma Termini train to NapoIi Metropark, bus to Naples airport, fly to Catania airport, bus to Catania Centrale, then train to Messina. 6hrs 29min 126 €.