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From Roma Termini train to Villa San Giovanni then ferry to Messina Marittima. 6hrs 14min 98 €. From Roma Ostiense train to Messina Centrale. 9hrs 28min 68 €. From Rome bus to Messina. 9hrs 33min 46 €. From Ara Coeli- Piazza Venezia line 492 bus to Rome, bus to Villa San Giovanni, Car ferry to San Francesco, then line 28 tram to Municipio. 11hrs 05min 59 €. From Rome rideshare to Messina. 7hrs 59min 34 €. From Rome drive to Messina. 8hrs 27min 133 €. From Roma Termini train to Rome airport, fly to Reggio Calabria airport, bus to Reggio di Calabria, then ferry to Messina. 6hrs 05min 83 €. From Roma Termini train to Rome airport, fly to Catania airport, bus to Catania Centrale, then train to Messina. 6hrs 41min 71 €. From Roma Termini train to Napoli Centrale, bus to Naples airport, fly to Catania airport, bus to Catania Centrale, then train to Messina. 6hrs 30min 125 €. From Roma Termini train to Rome airport, fly to Palermo airport, train to Palermo Centrale, then train to Messina. 8hrs 50min 91 €.

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