From Praha hl.n. train to Cheb, train to Kirchenlaibach, then train to Bayreuth Hbf. 5hrs 12min 590 Kč. From Florenc bus to Cheb, train to Marktredwitz, then train to Bayreuth Hbf. 5hrs 28min 721 Kč. From Praha, ÚAN Florenc bus to Nurenberg then bus to Bayreuth. 6hrs 47min 1 289 Kč. From Prague drive to Bayreuth. 2hrs 54min 1 202 Kč.