From Praha hl.n. train to Cheb, train to Kirchenlaibach, then train to Bayreuth Hbf. 5hrs 12min 577 Kč. From Prague Florenc bus to Cheb, train to Marktredwitz, then train to Bayreuth Hbf. 6hrs 18min 727 Kč. From Praha, ÚAN Florenc bus to Nurenberg then bus to Bayreuth. 6hrs 46min 1 283 Kč. From Prague drive to Bayreuth. 3hrs 36min 1 283 Kč.