From Praha hl.n. train to Cheb, train to Kirchenlaibach, then train to Bayreuth Hbf. 5hrs 12min 595 Kč. From Florenc bus to Cheb, train to Marktredwitz, then train to Bayreuth Hbf. 5hrs 28min 705 Kč. From Praha, ÚAN Florenc bus to Nurenberg then bus to Bayreuth. 6hrs 47min 1 301 Kč. From Prague drive to Bayreuth. 2hrs 54min 1 212 Kč.