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From Patmos ferry to Kos, car ferry to Bodrum, then drive to Izmir. 7hrs 51min 108€. From Patmos ferry to Pythagóreio, bus to Vathy, Samos, ferry to Kuşadası, then bus to Izmir. 7hrs 45min 52€. From Patmos ferry to Leros, taxi to Leros airport, fly to Izmir airport, then train to Izmir. 7hrs 17min 153€.

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