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From Patmos car ferry to Kalymnos, ferry to Bodrum, then drive to Izmir. 7hrs 18min 125€. From Patmos ferry to Pythagóreio, bus to Vathy, Ferry to Kuşadası, then bus to Izmir. 7hrs 15min 60€. From Patmos car ferry to Kalymnos, ferry to Turgutreis, bus to Soke, bus to Kuşadası, then bus to Izmir. 9hrs 59min 69€. From Patmos car ferry to Leros, taxi to Leros airport, fly to Izmir airport, then train to Izmir. 9hrs 21min 175€.

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