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From Patmos ferry to Kos, ferry to Bodrum, then drive to Izmir. 16hrs 01min 123 €. From Pátmos ferry to Pythagóreio, bus to Vathy, Samos, ferry to Kuşadası, then bus to Izmir. 7hrs 48min 49 €. From Patmos ferry to Kos, ferry to Bodrum, Bus to Soke, bus to Kuşadası, then bus to Izmir. 10hrs 04min 70 €.

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